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IIgANN TOKYO 2023

The 17th International Symposium on IgA Nephropathy (IIGANN 2023)

Suceena Alexander

Suceena Alexander

MBBS (Batch of 1995)

M.D., D.M. (Nephrology), FRCP (Lon), FASN, PhD.

Professor and HoU, Nephrology Unit III, Department of Nephrology, Christian Medical College, Vellore, Ranipet Campus – 632517, India.

Addl. Vice Principal (Research), Christian Medical College, Vellore – 632 004, India.

  • Early Career Fellow (Clinical and Public Health), DBT/ Wellcome Trust India Alliance (2015-2022)
  • Senior Fellow (Clinical and Public Health), DBT/ Wellcome Trust India Alliance (2023-2028)
  • Member, South Asia Regional Board, International Society of Nephrology
  • Associate Editor, Indian Journal of Nephrology

CONCURRENT APPOINTMENTS & COMMITTEE WORK

Deputy Director (Quality)

Quality Management Cell
Christian Medical College, Vellore
2016 – 2020

Examiner

BSc Dialysis Technology
The Tamil Nadu Dr. MGR Medical University, Chennai
2010 - present

Clinical Teacher

Medical Speciality
Christian Medical College, Vellore
2010 – present

Question Paper Setter

Nizam’s Institute of Medical Science Hyderabad, Telangana
2013 – present

Member

Institutional Review Board and Ethics Committee (Silver)
Christian Medical College, Vellore
2016 – present

Reviewer

  1. PLoS One
  2. Indian Journal of Nephrology
  3. International Urology and Nephrology
  4. Indian Journal of Transplantation
  5. BMC Nephrology
  6. Nephrology
  7. cJASN
  8. NephSap
  9. PLoS Global Health
  10. Kidney360

Course Co-ordinator

BSc Dialysis Technology
Christian Medical College, Vellore
2012 – present

Addl. Vice Principal (Research)

Christian Medical College, Vellore
2020 – present

PhD Co- Guide

The Tamil Nadu Dr. MGR Medical University, Chennai

DM/DNB Nephrology examiner

NBS, Delhi

Member Secretary

CMC Institutional Ethics Committee

Scientific Member

CMC Institutional Review Board

Member Secretary

CMC Institutional Patents Committee

Member Secretary

CMC Institutional Bio-Safety Committee

GRANTS

  • IRB Major Grant 2015 - Principal Investigator for project titled “GRACE- IgA Nephropathy Pilot Study”.
  • Wellcome UK DBT India Alliance Early Career Fellowship 2015-2020: Principal Investigator for project titled “Why is IgA nephropathy aggressive in Indians”. (http://www.wellcomedbt.org/)
  • ICMR SRF 2021-2023: Supervisor for project titled “Immuno Profiling in Focal Segmental Glomerulosclerosis: molecular pathways of progression approaches to cell specific identification by Multicolour Flow-cytometry analysis and T -Cell gene Signatures analysis by Microarray”.
  • ICMR Extramural Adhoc grant 2023-2026: PI for project titled “Diagnostic utility and clinical impact of genomic testing in adolescent and adult kidney disease patients with suspected monogenic etiology by establishing an integrated multi-institutional Kidney Genetics Service- a pragmatic prospective observational cohort study”.
  • Wellcome UK DBT India Alliance Senior Fellowship 2023-2028: Principal Investigator for project titled “Randomized Embedded Adaptive Platform Clinical Trial in South Asian Kidney Biopsy-Proven Primary Glomerular Diseases: Multi-center, Multi-arm and Multi-stage”. (http://www.wellcomedbt.org/)

Involvement in Clinical Trials

  1. Site Principal Investigator of our center (Christian Medical College, Vellore) for the multi-center RCT “A Phase 3, Multi-center, Randomized, Open- Label, Active-Controlled Study Evaluating the Safety and Efficacy of Roxadustat for the Treatment of Anemia in Dialysis Patients”- the study is completed.
  2. Site Principal Investigator of our center (Christian Medical College, Vellore) for the multi-center, randomized, double-blind, placebo-controlled, multiple dose study to evaluate the efficacy and safety of VIS649 in participants with Immunoglobulin A (IgA) nephropathy- completed.
  3. Site Principal Investigator of our center (Christian Medical College, Vellore) for the Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Atrasentan in Patients with IgA Nephropathy at Risk of Progressive Loss of Renal Function (The ALIGN Study)- ongoing.
  4. Site Principal Investigator of our center (Christian Medical College, Vellore) for the A Phase IIb Randomized, Double-Blinded, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of Atacicept in Subjects with IgA Nephropathy (ORIGIN Study)- ongoing.

Book publication

  1. Alexander S (2011). Lupus nephritis- advances in treatment. In Dakshinamurty KV, Raju TR, Deshpande P (Eds.), Postgraduate nephrology 2011 (pp.75-85). Hyderabad: Baxter India Pvt. Ltd.
  2. Jacob CK, Alexander S (2014). In Visweswaran KR (Ed.), Prescribing drugs in renal diseases 2014 (pp.44-54). Mumbai: True Life Media.
  3. Varughese S, Alexander S (2016). Nephropathy. In Thomas N, Kapoor N, Velavan J, Vasan S (Eds.), A practical guide to diabetes mellitus 2016 (pp.259-78). New Delhi: Jaypee Brothers Medical Publishers Pvt. Ltd.
  4. Alexander S, John GT (2020). Renal disease in the tropics. In Jeremy Farrar, Peter Hotez, Thomas Junghanss, Gagandeep Kang, David Lalloo, Nicholas J. White, Patricia Garcia (Eds.), Mason’s tropical diseases 24 edition: Elsevier (under review).

Membership in Professional Bodies

  1. International Society of Nephrology – Membership number 81511
  2. Indian Society of Nephrology – Membership number LM 983
  3. American Society of Nephrology - ASNID 158964, member since 2010
  4. Immunology Working Group, ERA-EDTA
  5. ERA-EDTA- Membership number 20241 since 2019
  6. Indian Society of Organ Transplantation since 2019
  7. Member ‘International IgA Nephropathy Network’