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Moderators

Hiromichi Wakui

Wakui, Hiromichi

  • Associate Professor,
    Department of Medical Science and Cardiorenal Medicine,Yokohama City University Graduate School of Medicine

Graduated from Yokohama City University School of Medicine in 2002, following which he completed two years of foundational clinical training. Subsequently, he pursued advanced clinical nephrology and hypertension practice at a prominent local hospital. In 2006, he matriculated into the Yokohama City University Graduate School of Medicine, dedicating his research to elucidating the regulatory mechanisms of renin-angiotensin receptor function in the context of hypertension and related cardiovascular and renal pathologies. His scholarly endeavors have consistently centered on the pathological regulation of cerebrovascular, cardiovascular, renal, metabolic, and endocrine diseases, leveraging insights from his initial molecular studies. Recently, he has commenced a randomized controlled trial investigating the effects of sodium zirconium cyclosilicate (SZC) on the quality of life in hyperkalemic patients undergoing maintenance hemodialysis. He is current position from April 2021.

1996-2002
Yokohama City University Graduate School of Medicine, Yokohama, JAPAN M.D.
Apr., 2002- Mar., 2004
Junior Resident in Medicine, Yokohama City University Hospital, JAPAN
Apr., 2004-Mar., 2005
Nephrology staff, Chigasaki Municipal Hospital, JAPAN
Apr., 2005-Mar., 2006
Nephrology staff, Yokohama Senin Hoken Hospital, JAPAN
Apr., 2006-Mar., 2010
Yokohama City University Graduate School of Medicine, Department of Medical Science and Cardiorenal Medicine, JAPAN. Ph.D.
Apr., 2010-Mar., 2017
Assistant Professor, Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, JAPAN
Apr., 2017-Mar., 2021
Lecturer, Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, JAPAN
Apr., 2021-
Associate Professor, Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, JAPAN

Current Highlight research:

  1. Research conducted on function-selective regulation of AT1 receptor signaling pathway in the renin-angiotensin system in hypertension and kidney diseases
  2. Research conducted on pathophysiological significance of diurnal blood pressure rhythm and blood pressure variability obtained by ABPM and HBPM in hypertension and kidney diseases
  3. Research conducted on elucidation of the cause of low quality od life (QOL) and improvement of QOL in patient with CKD
  4. Research conducted on elucidation of the molecular mechanism of apheresis treatment for PAD patients

Award:

2010 Best Paper Award of Graduate School of Yokohama City University
2019 Japanese Society of Nephrology, Oshima Award
2022 Japanese Society of Hypertension, Academic Award

Graduated from Yokohama City University School of Medicine in 2002, and after completing two years of initial clinical training, studied and practiced clinical nephrology and hypertension at a local core hospital. In 2006, he entered the Yokohama City University Graduate School of Medicine, where he focused on the regulation of renin-angiotensin receptor function in the pathogenesis of hypertension, as well as cardiovascular and renal diseases. Since then, he has consistently conducted research on the pathological regulation of cerebrovascular, cardiovascular, renal, metabolic, and endocrine diseases using this molecule as a stepping stone. He has recently initiated a randomized controlled trial of SZC on the quality of life in hyperkalemic patients undergoing maintenance hemodialysis. He is currently associated with the Department of Cardiorenal Medicine at Yokohama City University Graduate School of Medicine, JAPAN.